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An undead city under siege, soldiers and police ruthlessly shooting down waves of zombies that flood from infected streets, trying to escape and infect more cities.
在一座被围困的不死之城，士兵和警察无情击落从受感染的街道涌出的僵尸，这些僵尸试图逃跑并感染更多的城市。
This is what happens when your body fights cancer, more exciting than any movie. How does this battle for survival unfold?
这就是你的身体对抗癌症时发生的事情，比任何电影都更令人兴奋。这场生存之战是如何展开的？
1. The Elimination Phase. It all begins with a single corrupted cell. It is no longer able to repair its genetic code, it can't kill itself anymore and it is beginning to multiply rapidly.
1.消除阶段。一切都始于一个损坏的细胞。它不再能修复其遗传密码，它不能再自杀，并且它开始迅速繁殖。
At this point things are not great, not terrible – this cell is not yet dangerous but if nothing happens, it soon will be.
此时情况并不好，也不可怕——这个细胞还不危险，但如果什么都没有发生，很快就会变得危险。
Over a few weeks the corrupted cell keeps making copies of itself. One cell turns into dozens, hundreds, thousands.
几周后，损坏的细胞不断复制自身。一个细胞变成几十个、几百个、几千个。
Because the original was broken, its copies are breaking and mutating even more.
因为原来的细胞被破坏了，它的副本也破坏得更厉害，变异得也更多。
They turn into different genetic lineages, clans that are working together and competing.
它们变成了不同的遗传谱系，是一起工作和竞争的氏族。
Some mutate in a way that makes them weaker, others' mutations don't change anything, while a few become fitter and better at survival.
有些细胞发生变异，使自己变得更弱，而另一些细胞的变异不会改变任何东西，而有些细胞变得更健康，更善于生存。
Together they now form a tiny, tiny tumor. Not cancer yet, but getting there. The growing tumor needs a lot of resources.
它们现在一起形成了一个很小很小的肿瘤。还不是癌症，但正在变成癌症。不断增长的肿瘤需要大量资源。
If the cells don't get food and oxygen, they will die and the problem just solves itself.
如果细胞得不到食物和氧气，它们就会死亡，问题就会自行解决。
Unfortunately a few corrupted cells unlock a new mutation that saves them: The ability to order the growth of new blood vessels. And so your body provides the supply they need to survive.
不幸的是，一些受损的细胞解锁了一种新的突变，拯救了它们：命令新血管生长的能力。这样你的身体就会为它们提供生存所需的供应。
But as the tumor continues to grow, it starts causing damage – Neighbouring healthy cells begin to starve and die, which attracts attention. In a sense this tiny tumor is like a rogue town.
但随着肿瘤的不断生长，它开始造成损害——邻近的健康细胞开始挨饿和死亡，这引起了人们的注意。从某种意义上说，这个小肿瘤就像一个流氓小镇。
Imagine a group of rebels in Brooklyn decided that they were no longer part of New York but started a new settlement called Tumor Town, which happens to occupy the same space.
想象一下，布鲁克林的一群叛逆者决定他们不再是纽约的一部分，而是建立了一个名为肿瘤镇的新定居点，恰好占据了同样的空间。
The new city wants to grow, so it orders tons of steel beams, cement and drywall.
新城市想要发展，所以它订购了大量的钢梁、水泥和石膏板。
New buildings follow no logic, are badly planned, ugly and dangerously crooked.
新建筑毫无逻辑，规划糟糕，丑陋且歪斜危险。
They are built right in the middle of streets, on top of playgrounds and on existing infrastructure.
它们建在街道中间、操场上方和现有基础设施上。
The old neighborhood is torn down or overbuilt to make room for new stuff.
旧社区被拆除或过度建设，为新建筑腾出空间。
Many of the former residents are trapped in the middle of it and begin to starve.
许多前居民被困在其中，开始挨饿。
This goes on for a while until the smell of death finally attracts attention. Building inspectors and police show up.
这种情况持续了一段时间，直到死亡的气息终于引起注意。建筑检查员和警察出现了。
In your body, attracted by the stench of dead cells your immune system is activated.
在你的身体里，死细胞的恶臭会激活你的免疫系统。
First responder immune cells invade the tumor: Macrophages and Natural Killer Cells, police forces that go right to work, killing and eating tumor cells.
第一急救者免疫细胞侵入肿瘤：巨噬细胞和自然杀伤细胞，它们是立即开始工作的警察部队，杀死和吞噬肿瘤细胞。
They release chemical signals that let the whole immune system know that there is cancer to be eradicated.
它们释放化学信号，让整个免疫系统知道有癌症需要根除。
Dendritic Cells, the intelligence officers of your immune system, collect samples of dead tumor cells and begin activating your heavy weapons: Helper and Killer T Cells.
树突状细胞是免疫系统的情报官，它们收集死亡肿瘤细胞的样本并开始激活你的重型武器：辅助T细胞和杀伤T细胞。
We explained these specialized super weapons in another video, but all you really need to know is that they have a library listing every bad thing that could come into your body.
我们在另一个视频中解释了这些专门的超级武器，但你真正需要知道的是，它们有一个库，列出了可能进入你体内的所有坏东西。
While each cancer is unique, there are genetic corruptions that they can't hide. And your T Cells know what to look for. They are the deadliest cancer killers you have.
虽然每种癌症都是独一无二的，但存在着它们无法隐藏的基因腐败。而你的T细胞知道要寻找什么。它们是你体内最致命的癌症杀手。
By the time they arrive, the tumor has grown to hundreds of thousands of cells, but this is about to change.
当它们到达时，肿瘤已经长到数十万个细胞，但这种情况即将改变。
T Cells block the growth of new blood vessels, which starves thousands of tumor cells and puts an end to their growth.
T细胞阻止新血管的生长，使数千个肿瘤细胞挨饿并终止其生长。
Imagine the building inspectors, switching off electricity and water and putting up roadblocks to cancertown so no more food and materials can be delivered.
想象一下建筑检查员，切断水电，并在癌症城设置路障，这样就无法再运送食物和材料。
With no way to hide from the carnage unfolding, the tumor collapses as hundreds of thousands of tumor cells are massacred.
由于无法躲避正在展开的大屠杀，肿瘤崩溃了，数十万个肿瘤细胞被屠杀。
Their carcasses are cleaned up and consumed by Macrophages that then order healthy tissue to regenerate. Your body has crushed the illegal Tumor Town without mercy.
它们的尸体被巨噬细胞清理和吞噬，然后命令健康组织再生。你的身体毫不留情地粉碎了非法的肿瘤城。
You will never know about this fight or how many times this has happened inside your body. Except… in this case something did not go as planned.
你永远不会知道这场战斗，也永远不会知道这种战斗在你的身体里发生过多少次。只是……在这种情况下，有些事情没有按计划进行。
2. The Equilibrium Phase. Unfortunately, natural selection spoils your victory.
2.平衡阶段。不幸的是，自然选择破坏了你的胜利。
By doing its best to destroy the tumor, your immune system accidentally selects the fittest tumor cells.
你的免疫系统尽其所能摧毁肿瘤，却意外地选择了最适合的肿瘤细胞。
Remember, the tumor consists of different lineages that keep growing and keep mutating. Most of these are eradicated. But just a few are more resilient.
请记住，肿瘤由不同的谱系组成，它们不断生长和变异。其中大多数被根除。但只有少数细胞更有弹性。
One cell survives – it comes from the fittest tumor lineage and was just a bit better at surviving the massacre than anyone else. It decides to do it all over again.
一个细胞幸存了下来——它来自最适合的肿瘤谱系，在屠杀中比其他任何人都更能幸存下来。它决定再次这样做。
But better this time. This tumor cell is much stronger than any of the thousands that were killed. Maybe it is better at hiding, or fighting back.
但这次更好。这个肿瘤细胞比被杀死的数千个细胞都强壮得多。也许它更善于隐藏或反击。
Maybe it grows faster or is better at stealing resources. Maybe it can survive with much less oxygen. And so it all begins again.
也许它生长得更快，或者更善于窃取资源。也许它可以在氧气更少的情况下生存。于是一切又重新开始了。
