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演讲简介：
博妮·柏索发现细菌间是会交谈的，它们用一种化学语言来达到共同防卫，协同攻击的行为。这个发现对今后的医疗、工业有着重大的意义，包括怎样认识我们人类自己。
vi. 滑，滑动，滑入，悄悄地溜走
vt. 使
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- To finish I'll just show you the strategy.
- 最后，我只跟你们说一下战略。
- And this one I'm just using the interspecies molecule, but the logic is exactly the same.
- 在这里，我们只是使用跨菌种分子，但是思维逻辑是一模一样的。
- So what you know is that when that bacterium gets into the animal, in this case, a mouse, it doesn't initiate virulence right away.
- 你们都知道，当细菌进入动物体内，以此为例，对这只老鼠，它并不会马上启动致病机制。
- It gets in, it starts growing, it starts secreting its quorum sensing molecules.
- 它进入，开始增殖，开始分泌它的聚量感应分子。
- It recognizes when it has enough bacteria that now they're going to launch their attack, and the animal dies.
- 当累积到足够数量时，细菌能识别，并开始发起攻击，然后老鼠就死了。
- And so what we've been able to do is to give these virulent infections,
- 我们所做的是在致病感染的同时，
- but we give them in conjunction with our anti-quorum sensing molecules
- 加入我们的“反聚量感应分子”，
- so these are molecules that look kind of like the real thing, but they're a little bit different which I've depicted on this slide.
- 也就是看起来很像真的“聚量感应分子”的物质，但是，正如同我在幻灯上指出的，它们之间有一点点不同。
- And what we now know is that if we treat the animal with a pathogenic bacterium -- a multi-drug-resistant pathogenic bacterium
- 我们现在发现，如果让实验动物感染一种具有多重耐药性的致病细菌，
- in the same time we give our anti-quorum sensing molecule, in fact, the animal lives.
- 但是同时，我们施予“反聚量感应分子”治疗，动物就能够存活。
- And so we think that this is the next generation of antibiotics and it's going to get us around, at least initially, this big problem of resistance.
- 我们认为这应该是下一代的抗生素，它将能够让我们，至少在开始阶段，解决耐药性细菌的问题。
- So what I hope you think, is that bacteria can talk to each other, they use chemicals as their words,
- 我希望你们也能认为，细菌可以彼此交谈，它们使用化学物质当作语言，
- they have an incredibly complicated chemical lexicon that we're just now starting to learn about.
- 它们拥有极端复杂的化学语汇，我们现在才刚刚要开始学习这些语汇。
- And of course what that allows bacteria to do is to be multicellular.
- 当然，也因为这些语汇，使细菌得以变得像多细胞生物。
- Right? And so in the spirit of TED they're doing things together because it makes a difference.
- 所以，就像TED的精神一样，它们彼此合作，因为这样才能有一番作为。
- Right? So what happens is that bacteria have these collective behaviors
- 细菌因为有这些集体行为，
- and they can carry out tasks that they could never accomplish if they simply acted as individuals.
- 所以可以执行一些如果是单枪匹马是永远无法完成的任务。
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| 重点单词 | 查看全部解释 | |||
| slide | [slaid] | |||
| bacteria | [bæk'tiəriə] | |||
| virulent | ['virələnt] | 联想记忆 | ||
| accomplish | [ə'kɔmpliʃ] | 联想记忆 | ||
| initially | [i'niʃəli] | |||
| collective | [kə'lektiv] | 联想记忆 | ||
| logic | ['lɔdʒik] | 联想记忆 | ||
| molecule | ['mɔlikju:l] | |||
| complicated | ['kɔmplikeitid] | |||
| conjunction | [kən'dʒʌŋkʃən] | 联想记忆 |
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