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Fred and Betty: Is this the End? 
Episode 11: Betty's Had Enough
Betty: No Fred, it's over. I've given up on you.
GIVE UP ON
Meaning: to stop hoping that someone or something will change or improve 对...不再抱希望,不再相信,放弃
Grammar: This phrasal verb needs an object. You can not separate the verb from its particles.
I gave up on algebra - RIGHT
I gave up on it - RIGHT
I gave algebra up on - WRONG
I gave it up on - WRONG
I gave up algebra on - WRONG
I gave up it on - WRONG
