take a heavy toll (on somebody/something); take its toll (on somebody/something); to have a bad effect on somebody/something; to cause a lot of damage, deaths, suffering, etc. 产生恶果;造成重大损失(或伤亡、灾难等)
Illness had taken a heavy toll on her. 疾病对她的身体造成极大的损害.
The recession is taking its toll on the housing markets. 经济衰退使住房市场遭受着重大损失.
