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第239句 药物依赖
dependence is marked first by an increased tolerance, with more and more of the substance required to produce the desired effect, and then by the appearance of unpleasant withdrawal symptoms when the substance is discontinued.
译文：对药品的依赖性首先表现为不断增长的耐药量，要产生理想的效果所需的药品剂量越来越大，而一旦中断使用，就会出现痛苦的停药症状。
点睛：句子的主干结构是dependence is marked first by…，and then by...。逗号隔开的成分是with复合结构，with+名词+过去分词，作伴随状语，进一步解释药物依赖的第一种表现。when the substance is discontinued是时间状语从句。
另外注意名词在这里的特殊意义：dependence指“对药物的依赖，毒瘾”，withdrawal的意思是“停止用药”。
n. 依赖，信赖，上瘾
