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第750期:2011年 第三次病休(5)

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The gene sequencing and analysis were done collaboratively by teams at Stanford, Johns Hopkins, and the Broad Institute of MIT and Harvard.

基因排序和分析由斯坦福、约翰·霍普金斯和哈佛-麻省理工博德研究所的研究团队合作完成。
By knowing the unique genetic and molecular signature of Jobs's tumors,
了解乔布斯体内肿瘤的特殊基因和分子特征后,
his doctors had been able to pick specific drugs that directlytargeted the defective molecular pathways that caused his cancer cells to grow in an abnormal manner.
他的医生们就可以挑选特定的药品,直接针对导致他的癌细胞异常生长、有缺陷的分子位点进行治疗。
This approach, known as molecular targeted therapy, was more effective than traditional chemotherapy,
这种方法,称为分子靶向治疗法,比传统的化疗方法更为有效,
which attacks the process of division of all the body's cells, cancerous or not.
化疗会破坏身体里所有细胞的分裂过程,无论是癌细胞还是健康细胞。
This targeted therapy was not a silver bullet, but at times it seemed close to one:
这种靶_治疗并非药到病除,但时常效果显著:
It allowed his doctors to look at a large number of drugs -- common and uncommon, already available or only in development -- to see which three or four might work best.
它使医生可以筛选大量的药品--常见或不常见的,已经上市的或还在研制的--从中选出三四种可能最有效的。
Whenever his cancer mutated and repaved around one of these drugs, the doctors had another drug lined up to go next.
当他的癌细胞变异、一种药物不再有效时,医生们可以换下一种药物继续治疗。
Although Powell was diligent in overseeing her husband's care, he was the one who made the final decision on each new treatment regimen.
虽然鲍威尔谨慎地监管着丈夫的医护手段,但乔布斯是对每种新的治疗方案最后拍板的人。

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A typical example occurred in May 2011, when he held a meeting with George Fisher and other doctors from Stanford,

2011年5月发生了典型的一幕,乔布斯跟乔治·费希尔和其他斯坦福的医生、
the gene-sequencing analysts from the Broad Institute, and his outside consultant David Agus.
博德研究所的基因排序分析师,以及他的外部顾问戴维·阿古斯一起开了个会。
They all gathered around a table at a suite in the Four Seasons hotel in Palo Alto. Powell did not come, but their son, Reed, did.
他们都聚集在帕洛奥图四季酒店的一个套间里。鲍威尔没有来,但是儿子里德在场。
For three hours there were presentations from the Stanford and Broad researchers on the new information they had learned about the genetic signatures of his cancer.
在3个小时的会议中,斯坦福和博德的研究人员介绍了他们发现的他体内癌症基因特征的新信息。
Jobs was his usual feisty self. At one point he stopped a Broad Institute analyst who had made the mistake of using PowerPoint slides.
乔布斯情绪不安。博德研究所的一个分析师误用了PowerPoint幻灯片作介绍。
Jobs chided him and explained why Apple's Keynote presentation software was better; he even offered to teach him how to use it.
他训斥了他,解释为什么苹果的Keynote演示软件更好,甚至说要教他怎么用。
By the end of the meeting, Jobs and his team had gone through all of the molecular data,
会议结束时,乔布斯和他的团队已经了解了所有的分子数据,
assessed the rationales for each of the potential therapies, and come up with a list of tests to help them better prioritize these.
评估了每种潜在治疗方案的原理,并列出了要确定每种治疗方案优先级所需要作的测试。
One of his doctors told him that there was hope that his cancer, and others like it,
他的一位医生告诉他,有可能他的癌症和其他相似的癌症
would soon be considered a manageable chronic disease, which could be kept at bay until the patient died of something else.
很快会被归为可控制的慢性疾病,可以一直被遏制,直到他死于其他问题。
"I'm either going to be one of the first to be able to outrun a cancer like this,
“我要么就是最先这样跑赢癌症的人之一,
or I' m going to be one of the last to die from it," Jobs told me right after one of the meetings with his doctors.
要么就是最后死于这种癌症的人之一,”一次乔布斯跟医生们开会后这样告诉我。
"Either among the first to make it to shore, or the last to get dumped."
“不是最先上岸的,就是最后被淹死的。”

重点单词   查看全部解释    
available [ə'veiləbl]

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adj. 可用的,可得到的,有用的,有效的

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typical ['tipikəl]

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adj. 典型的,有代表性的,特有的,独特的

 
unique [ju:'ni:k]

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adj. 独一无二的,独特的,稀罕的

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abnormal [æb'nɔ:məl]

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adj. 反常的,不正常的,不规则的
n. 不

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manageable ['mænidʒəbəl]

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adj. 易办的,易管理的,易控制的

 
traditional [trə'diʃənəl]

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adj. 传统的

 
therapy ['θerəpi]

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n. 疗法,治疗

 
specific [spi'sifik]

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adj. 特殊的,明确的,具有特效的
n. 特

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institute ['institju:t]

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n. 学会,学院,协会
vt. 创立,开始,制

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analysis [ə'næləsis]

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n. 分析,解析

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